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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIN28
All Species:
20.91
Human Site:
S183
Identified Species:
38.33
UniProt:
Q9H9Z2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Z2
NP_078950.1
209
22743
S183
L
K
A
Q
Q
G
P
S
A
Q
G
K
P
T
Y
Chimpanzee
Pan troglodytes
XP_513232
209
22865
S183
L
K
A
Q
Q
G
P
S
A
Q
G
K
P
T
Y
Rhesus Macaque
Macaca mulatta
XP_001114640
143
15918
S117
L
K
A
Q
Q
G
P
S
A
Q
G
K
P
T
Y
Dog
Lupus familis
XP_854985
206
22464
S179
L
K
A
Q
Q
A
P
S
S
Q
G
K
P
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3Y3
209
22701
S183
L
K
A
Q
Q
G
P
S
S
Q
G
K
P
A
Y
Rat
Rattus norvegicus
P62961
322
35711
P248
P
R
F
R
R
G
P
P
R
Q
R
Q
P
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506004
274
29355
P193
H
K
T
G
A
Q
P
P
S
S
S
Q
G
R
P
Chicken
Gallus gallus
Q45KJ5
202
22071
S177
A
K
A
Q
Q
S
P
S
S
Q
G
K
P
A
Y
Frog
Xenopus laevis
Q8JHC4
195
21688
P169
N
H
M
V
A
Q
C
P
E
K
A
M
Q
A
A
Zebra Danio
Brachydanio rerio
Q803L0
202
21867
P175
I
K
A
Q
Q
L
S
P
G
S
Q
G
K
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRN5
195
21575
H165
H
L
H
A
D
C
P
H
K
N
V
T
Q
S
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P92186
227
25447
P190
E
R
R
R
K
H
R
P
E
Q
V
A
A
E
E
Sea Urchin
Strong. purpuratus
XP_792032
234
25286
G195
N
K
T
S
Q
G
N
G
S
N
G
S
G
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
65.5
95.2
N.A.
96.6
20.8
N.A.
53.2
80.8
62.6
66.9
N.A.
34.9
N.A.
26.4
33.7
Protein Similarity:
100
98.5
67.4
96.6
N.A.
98.5
34.4
N.A.
60.2
87
74.1
79.4
N.A.
47.8
N.A.
44
47
P-Site Identity:
100
100
100
80
N.A.
86.6
26.6
N.A.
13.3
73.3
0
26.6
N.A.
6.6
N.A.
6.6
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
53.3
N.A.
26.6
80
6.6
40
N.A.
20
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
54
8
16
8
0
0
24
0
8
8
8
31
8
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
16
0
0
0
0
8
16
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
47
0
8
8
0
54
8
16
0
8
% G
% His:
16
8
8
0
0
8
0
8
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
70
0
0
8
0
0
0
8
8
0
47
8
0
0
% K
% Leu:
39
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
16
0
0
0
0
0
8
0
0
16
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
70
39
0
0
0
0
54
0
8
% P
% Gln:
0
0
0
54
62
16
0
0
0
62
8
16
16
0
0
% Q
% Arg:
0
16
8
16
8
0
8
0
8
0
8
0
0
16
0
% R
% Ser:
0
0
0
8
0
8
8
47
39
16
8
8
0
24
0
% S
% Thr:
0
0
16
0
0
0
0
0
0
0
0
8
0
24
8
% T
% Val:
0
0
0
8
0
0
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _